Cost-Utility Analysis Of Apixaban In The Acute Treatment And Prevention Of Venous Thromboembolism In France.
نویسندگان
چکیده
SoC and SoC alone gained 0.3155 QALYs and 0.2752 QALYs, respectively. Hence, ranolazine plus SoC resulted in an ICER of € 4,620 per QALY gained, well below the threshold of € 34,000 per QALY gained, that is twice the annual per capita income. The PSA showed that the likelihood of ranolazine plus SoC being cost-effective at the threshold of € 34,000 per QALY gained was 100%. ConClusions: The results suggest that ranolazine as add–on treatment may be a cost-effective alternative for the symptomatic treatment of patients with chronic stable angina in Greece.
منابع مشابه
Cost-effectiveness analysis of apixaban compared to low-molecularweight heparins and vitamin k antagonists for treatment and secondary prevention of venous thromboembolism.
OBJECTIVE Cost-effectiveness analysis of a 6-month treatment of apixaban (10 mg/12h, first 7 days; 5 mg/12h afterwards) for the treatment of the first event of venous thromboembolism (VTE) and prevention of recurrences, versus low-molecular-weight heparins/vitamin K antagonists treatment (LMWH/VKA). MATERIAL AND METHODS A lifetime Markov model with 13 health states was used for describing the...
متن کاملClinical utility of apixaban in the prevention and treatment of venous thromboembolism: current evidence
Anticoagulation with heparin and vitamin K antagonist has been the mainstay of prevention and treatment of venous thromboembolism (VTE) for many years. In recent years, novel oral anticoagulants such as dabigatran etexilate (a direct thrombin inhibitor) and rivaroxaban, apixaban, and edoxaban (a direct factor Xa inhibitor) have emerged for the prevention and treatment of VTE. Novel oral anticoa...
متن کاملCost-effectiveness of apixaban versus low molecular weight heparin/vitamin k antagonist for the treatment of venous thromboembolism and the prevention of recurrences
BACKGROUND Prior analyses beyond clinical trials are yet to evaluate the projected lifetime benefit of apixaban treatment compared to low-molecular-weight heparin (LMWH)/vitamin K antagonist (VKA) for treatment of venous thromboembolism (VTE) and prevention of recurrences. The objective of this study is to assess the cost-effectiveness of initial plus extended treatment with apixaban versus LMW...
متن کاملA New Cost-Effectiveness Modelling Approach In Chronic Heart Failure With Reduced Ejection Fraction.
analysis was to develop two cost effectiveness models taking into account the new management of the treatment of AF and VTE in France. The clinical and cost benefits of VKA (with/without the use of a PAS) has been evaluated versus new oral anticoagulants (NOAC): dabigatran, rivaroxaban and apixaban. Methods: A Markov model was built for the treatment of AF and a decision tree for the treatment ...
متن کامل[Cost-effectiveness analysis of apixaban compared to dabigatran in the prevention of venous thromboembolism in patients subjected to total knee or hip replacement].
OBJECTIVE Cost-effectiveness analysis of apixaban vs. dabigatran in preventing venous thromboembolism (VTE) in total knee (TKR) or hip (THR) replacement. METHODS Model with two periods: post-prophylaxis period of 90 days (short term) and 5 years (Markov). VTE complications (distal and proximal deep vein thrombosis, pulmonary embolism, bleeding and post-thrombotic syndrome) were included. The ...
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ورودعنوان ژورنال:
- Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
دوره 18 7 شماره
صفحات -
تاریخ انتشار 2015